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Description
Ranexa 375mg is used in combination with other medicines to treat chest pain, the discomfort that you finger anywhere withal the upper part of your soul between your neck and upper abdomen, often brought on by exercise or too much activity. By reducing the flow of calcium into the cells, Ranexa is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

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How Does Ranexa 375mg Work?

Ranexa 375 mg is used to treat chronic angina (chest pain). It may be used with beta-blockers, nitrates, calcium channel blockers, anti-platelet therapy, lipid-lowering therapy, ACE inhibitors, and angiotensin receptor blockers.

Ranexa 375 mg is an anti-anginal medication. It works by improving blood flow to help the heart work more efficiently.

Ranexa 375 mg is used to treat chronic angina (chest pain). Ranexa 375 mg is not for use during an acute (emergency) angina attack.

Ranexa 375 mg may also be used for purposes not listed in this medication guide.

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What Are Side Effects of Ranexa?

Common side effects of Ranexa include
dizziness,
spinning sensation,
nausea,
vomiting,
stomach pain,
constipation,
headache,
dry mouth,
weakness,
ringing in your ears,
swelling in hands/ankles/feet,
slow/fast/irregular heartbeats,
tremors,
blood in the urine, and
shortness of breath.

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Dosing Information

Based on clinical symptoms, initiate Ranexa 375 mg dosing at 500 mg twice daily and increase to 1000 mg twice daily, as needed. Take Ranexa 375 mg with or without meals. Swallow Ranexa 375 mg tablets whole; do not crush, break, or chew.

The maximum recommended daily dose of Ranexa 375 mg is 1000 mg twice daily.

If a Ranexa 375 mg is missed, take the prescribed dose at the next scheduled time; do not double the following amount.

Dose Modification

Dose adjustments may be needed when Ranexa 375 mg is taken in combination with certain other drugs. The use of Ranexa 375 mg with potent CYP3A inhibitors is contraindicated. P-GP inhibitors, such as cyclosporine, may increase exposure to Ranexa 375 mg. Titrate Ranexa 375 mg based on clinical response.

Dosage Forms And Strengths

Ranexa 375 mg is supplied as film-coated, oblong-shaped, extended-release tablets in the following strengths:

500 mg tablets are light orange, with GSI500 on one side

1000 mg tablets are pale yellow, with GSI1000 on one side

Storage And Handling

Ranexa 375 mg is supplied as film-coated, oblong-shaped, extended-release tablets in the following strengths:

500 mg tablets are light orange, with GSI500 on one side

1000 mg tablets are pale yellow, with GSI1000 on one side

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